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This site complies with the HONcode standard for trustworthy health information: verify here. In rare cases, rivaroxaban can cause a serious allergic reaction anaphylaxis. These are not all the side effects of rivaroxaban. For a full list, see the leaflet inside your medicines packet. Rivaroxaban is not normally recommended during pregnancy or while breastfeeding. Tell your doctor if you're taking these medicines before starting rivaroxaban:.
You can take paracetamol while you're taking rivaroxaban. Do not take aspirin or ibuprofen while you're taking rivaroxaban unless a doctor has said it's OK to. They increase the chance of bleeding. Do not take St John's wort, the herbal remedy for depression, while you're taking rivaroxaban. Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. Rivaroxaban is a type of medicine known as an anticoagulant. It makes your blood clot more slowly.
Blood clotting thickening is a complicated process involving substances called clotting factors. Clotting factors are made by the liver and help stop bleeding. They work with blood cells called platelets that trigger the clotting process to make sure your blood clots properly. Rivaroxaban works by stopping a clotting factor called factor Xa from working. This thins your blood so it takes longer to clot.
There do not seem to be any lasting harmful effects from taking it for many months and years. If you stop taking rivaroxaban, the rate at which your blood clots will return to what it was before you started taking it, usually within a day or two of stopping. This means you may be at increased risk of serious problems like strokes , heart attacks , DVT or pulmonary embolism.
They include apixaban , dabigatran , edoxaban and warfarin. There are also anticoagulants that you take by injecting them. These include heparin, enoxaparin, dalteparin and tinzaparin. Talk to your doctor or pharmacist to find out why you have been recommended a particular medicine. You can drink alcohol while taking rivaroxaban as long as you stick to the national guidelines of no more than 14 units a week for men and women.
A standard glass of wine ml is 2 units. A pint of lager or beer is usually 2 to 3 units of alcohol. Drinking heavily, especially binge drinking lots of alcohol in one go, is dangerous while taking rivaroxaban.
The alcohol can increase rivaroxaban's effect and make you more likely to bleed. Because of the risk of bleeding, your dose of rivaroxaban may need to be lowered or stopped a few days before you have an operation. Tell the surgeon that you're taking rivaroxaban and show them your anticoagulant alert card. You can still go to your dentist as usual. But tell your dentist that you're taking rivaroxaban, and show them your anticoagulant alert card, before you have any treatment.
Most people do not need to change their rivaroxaban dose, but your dentist may contact your doctor for advice before starting the dental treatment. Before you have them, be sure to show your anticoagulant alert card to the nurse or doctor.
Rivaroxaban does not affect any type of contraception, including the combined pill and emergency contraception. There's no firm evidence to suggest that taking rivaroxaban will reduce fertility in either men or women. But talk to your doctor first if you're a woman and trying to get pregnant. But if taking rivaroxaban makes you feel dizzy or lightheaded, do not drive or cycle until it goes away.
It's not usually recommended to have a body piercing or tattoo while you're taking rivaroxaban because of the increased risk of bleeding and infection. If you still want to go ahead, talk to your doctor about your specific risks in case you need antibiotics. And let the tattooist or piercer know beforehand that you're taking a blood-thinning medicine. It's thought that cannabis can increase your risk of serious bleeding. It's not clear how other recreational drugs like cocaine and heroin affect rivaroxaban.
They could be potentially dangerous. You can reduce your risk of having a blood clot by making changes to your lifestyle, such as:. Page last reviewed: 12 April Next review due: 12 April Rivaroxaban On this page About rivaroxaban Key facts Who can and cannot take rivaroxaban How and when to take it Bleeding and what to do about it Other side effects How to cope with side effects Pregnancy and breastfeeding Cautions with other medicines Common questions.
About rivaroxaban Rivaroxaban is a type of medicine known as an anticoagulant, or blood thinner. People who are more at risk of developing a blood clot include those who have: an abnormal heartbeat atrial fibrillation recently had surgery to replace a hip or knee joint unstable angina coronary heart disease peripheral artery disease It's also used to treat people who have had a health problem caused by a blood clot, such as: a stroke a heart attack a blood clot in the leg DVT, deep vein thrombosis a blood clot in the lungs pulmonary embolism Rivaroxaban is only available on prescription.
It comes as tablets. Help us improve our website Can you answer a quick question about your visit today? It's usual to take rivaroxaban once or twice a day.
Take rivaroxaban just after you have eaten a meal or snack. It's important to take it with food to help your body absorb the whole dose. The most common side effect of rivaroxaban is bleeding more easily than normal, such as having nosebleeds, heavier periods, bleeding gums and bruising.
It tends to happen in the first few weeks of treatment or if you're unwell. Always carry your anticoagulant alert card with you. Show it to your doctor or dentist before you have surgery or dental treatment. It's important they know you're taking rivaroxaban, as it may put you at risk of bleeding. Rivaroxaban is also called by the brand name Xarelto. Rivaroxaban can be taken by adults aged 18 and over.
Rivaroxaban is not suitable for some people. You are viewing BNF. A phase 3 clinical trial showed that the risk of all-cause death and bleeding after transcatheter aortic valve replacement TAVR approximately doubled in patients assigned to a rivaroxaban-based anticoagulation strategy compared with those receiving an antiplatelet-based strategy clopidogrel and aspirin. The MHRA reminds healthcare professionals that rivaroxaban should not be used for thromboprophylaxis in patients with prosthetic heart valves, including patients who have undergone TAVR.
Rivaroxaban treatment in patients who undergo TAVR should be stopped and switched to standard of care. A clinical trial has shown an increased risk of recurrent thrombotic events associated with rivaroxaban compared with warfarin, in patients with antiphospholipid syndrome and a history of thrombosis.
There may be a similar risk associated with other DOACs. Healthcare professionals are advised that DOACs are not recommended in patients with antiphospholipid syndrome, particularly high-risk patients who test positive for all three antiphospholipid tests—lupus anticoagulant, anticardiolipin antibodies, and anti-beta 2 glycoprotein I antibodies. Continued treatment should be reviewed in these patients to determine if appropriate, and switching to a vitamin K antagonist such as warfarin should be considered.
In those who have difficulty swallowing, these tablets can be crushed and mixed with water or apple puree immediately before, and followed by food immediately after, ingestion. The MHRA reminds healthcare professionals to remain vigilant for signs and symptoms of bleeding complications during treatment with rivaroxaban after ongoing reports of serious, potentially fatal bleeds associated with the use of DOACs. Healthcare professionals are also advised to use rivaroxaban with caution in patients with increased bleeding risk, and to ensure that those with renal impairment are dosed appropriately and their renal function monitored during treatment.
Patients should be counselled on the signs and symptoms of bleeding, and encouraged to read the patient information leaflet. Active bleeding ; antiphospholipid syndrome increased risk of recurrent thrombotic events ; malignant neoplasms at high risk of bleeding ; oesophageal varices ; prosthetic heart valve efficacy not established ; recent brain surgery ; recent gastro-intestinal ulcer ; recent intracranial haemorrhage ; recent ophthalmic surgery ; recent spine surgery ; significant risk of major bleeding ; vascular aneurysm.
When used for prophylaxis of atherothrombotic events following an acute coronary syndrome. When used for prophylaxis of atherothrombotic events in patients with coronary artery disease or symptomatic peripheral artery disease.
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